An Introduction to Psychopathy

I am still surprised by the amount of disagreement about psychopathy, sociopathy, antisocial personality disorder, etc. that you'll get from any source -- academic, pop psychology, etc. With that small caveat (nothing is definitive), I found this article on psychopathy to be a good overview with academic cites (and links in the original). Here are some selections:

While it is past antisocial behavior that is particularly important in predicting future criminal activity (Walters, 2003), it is CU (callous unemotional) traits that are at the core of developmental trajectory associated with psychopathy (Frick and White, 2008). The disorder is developmental. It has been shown that CU traits in particular and the psychopathy more generally are relatively stable from childhood into adulthood (Lynam et al., 2007; Munoz and Frick, 2007). In addition, the functional impairments seen in adults with psychopathy (e.g., in responding to emotional expressions, aversive conditioning, passive avoidance learning, reversal learning, extinction) are also seen in adolescents with psychopathic tendencies (see later).
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Psychopathy is not equivalent to the psychiatric conditions of conduct disorder (CD) or antisocial personality disorder (ASPD) as defined by DSM-5 or their ICD-10 counterparts. The diagnostic criteria for these disorders focus on antisocial behaviors rather than on etiological factors such as the emotion dysfunction seen in psychopathy (Blair et al., 2005). As such these psychiatric conditions describe individuals with difficulties in executive dysfunction (Moffitt, 1993), as well as individuals with symptoms stemming from CU traits. Consequently, individuals with psychopathy are a more homogenous group than those individuals meeting the criteria for CD and ASPD (Karnik et al., 2006). It should be noted, however, that DSM-5 includes the specifier for CD ‘with limited pro-social emotions,’ which stem directly from research on youth with CD and CU traits (Pardini et al., 2010; Pardini and Fite, 2010). Furthermore, the diagnosis of ASPD now includes components of psychopathy (APA, 2013). While the disorder of psychopathy will still not be equivalent to the DSM-5 diagnoses of CD and ASPD, there will be greater overlap in diagnostic conceptualization.

Psychopathy is characterized by an increased risk for antisocial behavior (Frick and Dickens, 2006; Hare, 2003). While several psychiatric disorders and neurological conditions, including CD and ASPD (APA, 2013), confer an increased risk of reactive aggression (Anderson et al., 1999; Leibenluft et al., 2003), psychopathy is unique in that it conveys increased risk for instrumental aggression (Frick et al., 2003). 

Interestingly, an article that was cited included this assessment of treatment options: "While treatment recommendations are currently sparse, recent work has shown that previous assessments of treatment amenability in this population may have been overly pessimistic."

Also, because I had to look this up too:
"A classic measure of stimulus-reinforcement learning is aversive conditioning -- the individual learns that a particular stimulus is associated with threat. Individuals with elevated CU traits show marked impairment in stimulus-reinforcement learning. Indeed, an individual's ability to perform aversive conditioning at 15 years has predictive power regarding whether that individual will display anti-social behavior 14 years later (Raine et a., 1996)."

Right brained (part 1)

This is a somewhat old study done by ex-USC research Adrian Raine that suggests that the difference between high functioning "successful" sociopaths and low functioning "unsuccessful" sociopaths might actually be neurological:

He tested the theory that psychopaths with hippocampal impairments could become insensitive to cues that predicted punishment and capture. As a result, he said, these “impaired’ psychopaths were more likely to be apprehended than psychopaths without that deficit.

Fewer than half of both the control subjects and the “successful” psychopaths had an asymmetrical hippocampus.

Ninety-four percent of the unsuccessful psychopaths had that same abnormality, with the right side of the hippocampus larger than the left.

Raine said the results suggest, but don’t prove, a neuro-developmental root for psychopathy.

In a second study, he looked at the corpus callosum of both types of sociopaths, and found that they are both longer and thinner than that of the average neurotypical:

The corpus callosum is a bundle of nerve fibers that connects the two hemispheres of the brain, enabling them to work together to process information and regulate autonomic function. Raine explored its role in psychopathy for the first time.
“There’s faulty wiring going on in psychopaths. They’re wired differently than other people,” Raine said. “In a way, it’s literally true in this case.”

He found that the psychopaths’ corpus callosums were an average of 23 percent larger and 7 percent longer than the control groups’.

“The corpus callosum is bigger, but it’s also thinner. That suggests that it developed abnormally,” Raine said.

The rate that the psychopaths transmitted information from one hemisphere to the other through the corpus callosum also was abnormally high, Raine said.

Of course they don't credit the sociopath brain as having an advantage over a neurotypical brain, despite the demonstrated greater efficiency in transmitting information between brain hemispheres. Instead this efficiency is vaguely insinuated as the cause for the sociopath's "less remorse, fewer emotions and less social connectedness - the classic hallmarks of a psychopath."

Normal people, even scientists, won't ever admit that a sociopath's brain might actually be better. Every single article I have seen that even comes close to discussing some of the advantages of the sociopathic brain eventually backs off and makes some pat conclusion about how broken we are. In fact, the title of the article is "Out of Order." But there are two meanings to that phrase, and I think only one of them applies to this sort of bias thinly masked as science.